CJC 1295-Ipamorelin

CJC-1295 causes the natural release of GH, but it does so by naturally stimulating the growth hormone releasing hormone receptor. CJC-1295 is a synthetic peptide that mimics growth hormone-releasing hormone (GHRH). It binds to pituitary receptors to stimulate GH secretion, which in turn increases insulin-like growth factor-1 (IGF-1) levels. First developed in the 1980s, research studies have shown it to improve muscle repair and growth, accelerate wound healing, strengthen bones, increase fat burning, and improve metabolism. It may also have beneficial effects on blood sugar regulation and the immune system.

Ipamorelin is one of the most selective growth hormone (GH) secretagogues known and a potent agonist of the ghrelin/growth hormone secretagogue receptor. It has been heavily researched in a number of settings and is known to, improve bone health, boost muscle repair and development, stimulate insulin release from the pancreas, and improve bowel motility and gastric function. Ipamorelin is a pentapeptide that mimics ghrelin, targeting ghrelin receptors to stimulate GH release without affecting cortisol or prolactin levels. Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that mimics ghrelin, a hormone that stimulates the release of growth hormone from the pituitary gland. It is known for its high potency and efficacy in releasing GH without significantly affecting other hormones like ACTH or cortisol, making it a unique candidate among growth hormone secretagogues.

CJC-1295 when combined with Ipamorelin has been shown to exhibit synergistic effects when researched together. 

The key characteristics:

  • A 1:1 blend of CJC-1295 No DAC (5mg) and Ipamorelin (5mg) designed to optimize growth hormone (GH) release, promoting muscle growth, fat loss, and enhanced tissue repair.
  • CJC-1295 No DAC stimulates natural GH pulses with extended activity, mimicking physiological GH release patterns for balanced and sustained anabolic effects.
  • Ipamorelin selectively triggers potent GH release via the ghrelin receptor, minimizing side effects on cortisol and prolactin levels for a cleaner hormonal profile.
  • This synergistic combination enhances lean muscle mass, improves recovery, boosts fat metabolism, and supports anti-aging benefits through increased collagen production.
  • Ideal for advanced users looking to achieve optimized anabolic responses, faster recovery, and improved body composition without disrupting hormonal balance.

Citations

  1. Peptides.org monograph: CJC-1295 No DAC is a short-acting GHRH(1–29) analogue (half-life ~30 min), distinct from DAC variant. Blend Overview – GH-axis Synergy
  2. Peptides.org: “CJC-1295 No DAC: Modified GRF(1–29) mimics endogenous GHRH pulse, ideal for acute GH-axis studies.” Blend Overview – GH-axis Synergy
  3. PubChem Compound Summary for Ipamorelin (CID 9831659): sequence Aib–His–D-2-Nal–D-Phe–Lys–NH2; formula C38H49N9O5; MW 711.9 Da. Blend Overview – GH-axis Synergy
  4. Peptides.guide entry: Ipamorelin is a selective GHSR agonist promoting GH release without cortisol/prolactin release, used in muscle growth and body composition research. Blend Overview – GH-axis Synergy

This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.

This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.